JEOL USA Press Releases

JEOL (President & CEO Izumi Oi) announced the release of the "ROYAL PROBE™ AUTOMAS", a high-throughput solid-state NMR probe for nuclear magnetic resonance (NMR) systems, on 1st July 2024.

The ROYAL PROBE™ AUTOMAS is the successor to the AUTOMAS probe, which was launched in 2018 as a high-throughput solid-state NMR probe.

The AUTOMAS probe, in combination with the NMR software Delta, the Auto Sample Changer (ASC), and the Auto-Tuning Unit, allows multiple samples to be measured in series.

In addition to the basic functions of the AUTOMAS probe, the ROYAL PROBE™ AUTOMAS adds new features such as a seamless tuning range with the slider unit, automatic magic angle adjustment, and an extended measurement temperature range. These improvements dramatically enhance ease of use and make solid-state NMR measurements more accessible.

JEOL Ltd. (President & CEO Izumi Oi) announced the release of High Sensitivity COOL Probe "SuperCOOL MARVEL" for Nuclear Magnetic Resonance, NMR, on July 1st, 2024. Its sales are scheduled to begin in October 2024.

SuperCOOL MARVEL is the fourth generation of the SuperCOOL probe series, which was launched in 2013. The SuperCOOL probe series suppresses thermal noise and enables highly sensitive NMR measurements by cooling the RF coil and preamplifier to liquid nitrogen temperature. This product not only utilizes the low-temperature cooling technology know-how that we have cultivated over many years, but also achieves a significant improvement in sensitivity by completely redesigning the electrical circuitry inside the probe.

SuperCOOL MARVEL, which can measure low noise and high sensitivity, is a multi-nuclear probe capable of measuring not only common nuclei such as 1H and 13C, but also nuclei such as 19F and 31P. It is highly effective in measuring samples that decompose or change quickly, as well as trace samples that are difficult to obtain.

JEOL (President and CEO: Izumi Oi) announces the release of the new electron microscope JEM-120i developed with the concepts of "Compact", "Easy To Use", and "Expandable" on May 30, 2024.

Electron microscopes are utilized in a wide range of fields from biotechnology to nano technology, polymers, and advanced materials. With the expansion of application, usages are also expanding, which requires a tool that is easy-to-use for research and testing purposes. To satisfy such needs, the JEM-120i has evolved into a next-generation microscope that is easy to use, from operation to maintenance, for both beginner and experienced users.

Main Features

Compact

The JEM-120i adopts a totally new appearance and compact design that fits any installation location. The footprint has been reduced by more than 50%, and the volume occupied by the instrument is less than one-third of that of conventional models, enabling effective use of space. The instrument height is lower than 1,800 mm, which fits just about any installation room.

Easy to Use

The enhanced TEM control system and fully automated apertures eliminated the need for switching the magnification mode and selecting an aperture. The JEM-120i provides seamless observations from low to high magnification.

It takes only 4 steps from loading a specimen to completing an observation. After inserting the specimen holder, clicking the Start Button automatically performs observation preparation operations such as voltage increase and emission start. A wide area image is captured at the same time, and clicking the target field of view will complete the stage movement. Standard "Butler mode" assists data acquisition. Even a beginner can capture data easily.

Expandable

In addition to the standard multi-function camera, a bottom-mount camera of higher pixel count can be selected as an option.

Attachments such as the scanning image observation function (STEM), elemental analysis function (EDS), and cryo observation function can be applied, regardless of instrument configuration. The instrument can be expanded at any time to meet the changing needs of microscopy over time.

The proven scripting function (PyJEM) with the high-end models, can create an algorithm for automation. The automation can increase the utilization rate of the instrument and improve data output efficiency.

Main Specifications

*1 (HC) : High contrast configuration
*2 (HR) : High resolution configuration

JEOL is pleased to announce the introduction of a new CRYO-FIB-SEM, a Focused Ion Beam milling specimen preparation tool specifically designed for creating thin, frozen samples for Cryo-Electron Microscopy. The new system complements JEOL’s existing Cryo-TEM technology and provides a comprehensive solution for preparing and imaging vitreous frozen biological and biopolymer samples to be observed in the CRYO ARM 200 and CRYO ARM 300II Transmission Electron Microscopes. 

JEOL’s CRYO-FIB-SEM incorporates a liquid nitrogen cooling stage and a cryocooled specimen transfer mechanism for optimum specimen handling. The CRYO-FIB-SEM has a built-in sputter coating function, making it possible to perform conductivity coating, protective film forming, and FIB processing in a single system. 

Additionally, the workflow is based on JEOL's specially-designed CRYO ARM™ cartridge, allowing direct specimen transfer to the CRYO ARM™ after specimen preparation with the CRYO-FIB-SEM. A cryo-CLEM workflow using the CRYO ARM™ cartridge can be constructed using a cryostage manufactured by Linkam Scientific Instruments* and a fluorescence microscope manufactured by Nikon Solutions*. The stage coordinates of each instrument can be linked, so the orientation and position of the specimen can always be identified during specimen transfer between instruments.

Using Cryo-EM, researchers can capture high resolution details of proteins and biological specimens. With the advent of the resolution revolution for Cryo-EM beginning around 2010, JEOL CRYO ARM TEMs continue to solve structures previously reserved for traditional X-Ray Crystallography. Imaging data achieved at rapid speeds can be used to create 3D reconstructions of viruses and proteins. Data can also be interpreted using Single Particle Analysis, MicroED using electron diffraction from 3D crystals, electron crystallography, and tomography. 

“Along with the CryoARM, the CryoFIB now closes the loop in the cryo-EM process to provide a solution that is completely JEOL. This will streamline the entire cryo-EM process, from sample preparation to data collection,” said JEOL TEM Product Manager Dr. Patrick Phillips. 
Learn more >

Peabody, MA | Nov. 2, 2023 – JEOL’s JAM-5200EBM Metal 3D Printer, a production ready Electron Beam Powder Bed Fusion (EB-PBF) additive manufacturing solution, has demonstrated the ability to meet the rigorous AMS7032 operational qualification (OQ) standards, while achieving the AMS7011 material requirements for Ti-6Al-4V alloy with post-deposition hot isostatic pressing (HIP). JEOL’s is the first EB-PBF machine known to meet the requirements of AMS7011 since they were first established on another EB-PBF manufacturer’s model.

The AMS7032 Operational Qualification Standard evaluates the ability of an AM powder bed fusion machine to consistently meet material specification requirements while maintaining process control and stability over several builds. To comply with the OQ procedures listed in AMS7032, three identical builds containing a large number of Ti-6Al-4V specimens in all three orientations and encompassing the entire JAM-5200EBM build envelope were made using reused powder that conformed to the AMS7015 specification. The specimens were then subjected to tensile testing, microstructure evaluation, chemical composition testing, radiography, and other tests to verify that they met the requirements of AMS7011. All required post processing and testing of the specimen was performed at a ISO17025 accredited laboratory.

The results of the testing not only demonstrated the high stability of the machine, but also revealed a key strength of this system: the JEOL JAM-5200EBM system produces material with excellent ductility and very low anisotropy. These results also indicate that designers should have significant freedom in how parts are oriented within the build envelope thus enabling greater DfAM flexibility and unlocking the potential for truly optimized designs.

“JEOL has provided metrology, analytical, and electron beam manufacturing instruments for over seventy years and understands that manufacturers must have confidence in their tools,” shares Bob Pohorenec, President of JEOL USA. “Meeting the AMS7032 operational qualification standard ensures manufacturers that the JAM-5200EBM is capable of producing aerospace-grade material with stable performance and meets all material specification requirements. This achievement is a testament to our commitment to quality and reliability.”

For businesses operating in the aerospace industry, our efforts greenlight a new alternative for 3D metal printing of parts essential in the manufacturing process. This grants them access to JEOL’s more than 70 years of electron beam expertise and grants the peace of mind that parts will meet compliance standards set in place to avoid failures.

JEOL is excited to share the insights and outcomes of its success meeting the qualification standards of AMS7032 and the material requirements of AMS 7011 with the wider community. The results were first presented at the Fall meeting of the SAE AMS AM Additive Manufacturing Metals committee, and the NRC Workshop on Advanced Manufacturing Technologies for Nuclear Applications, both held in October.

JEOL will further host a webinar on December 5th at 2PM ET, offering an in-depth discussion of the results, capabilities, and future prospects of this cutting-edge AM system. Furthermore, JEOL will be actively participating at Formnext 2023, providing an opportunity for industry professionals to meet their R&D team and learn more about their technology.

Pittsburgh, PA | Oct 4, 2023– JEOL, a world-renowned leader in electron optics and advanced technology solutions, proudly announces the arrival of the JAM-5200EBM Electron Beam-Powder Bed Fusion system to Cumberland Additive located at Neighborhood 91, the advanced manufacturing production campus at Pittsburgh International Airport. JEOL's leadership joined the Cumberland team this week to formally introduced the JAM-5200EBM to invited guests.

The JAM-5200EBM made an impressive debut in North America as the system was fully operational within just six days of arrival, a testament to its engineering excellence. The JEOL team further demonstrated its capabilities by producing an AMS 7032 compliant build within three weeks of installation, generating valuable data on the system's performance and repeatability across various build geometries. The same JAM-5200EBM machine had already completed an operational qualification per AMS 7032 specification at its manufacturing factory site in Japan where the results demonstrated that the machine is capable of meeting AMS 7011 specification minimums for Electron Beam-Powder Bed Fusion machines.

Cumberland Additive CEO Dawne Hickton officially welcomed JEOL to the production floor in Neighborhood 91 commenting, “This collaboration with JEOL signifies a new era in advanced additive manufacturing at Neighborhood 91. We look forward to harnessing the capabilities of the JAM-5200EBM E-Beam system and unlocking new possibilities in the world of materials science and 3D printing."

JEOL USA President Robert Pohorenec highlighted the significance of this partnership and the revolutionary advancements in additive manufacturing technology that JEOL is bringing to the table, “JEOL has been the leading supplier of electron-beam based imaging instruments and manufacturing tools for seventy-five years and has a well-established global customer service organization. However, we are a relative newcomer to the additive manufacturing machine market. The opportunity to collaborate with an additive manufacturing leader like Cumberland Additive in the Neighborhood 91 Additive Manufacturing campus provides us the perfect partner and location to introduce the JAM-5200EBM electron beam system in North America and to demonstrate our commitment to customer service.”

The JAM5200EBM system will initially focus on Titanium alloy, but the system is easily adaptable with the addition of a second hopper and feeder system. This will enable a seamless transition to produce components in Pure Copper and Nickel 718 alloy, expanding the range of possibilities for Neighborhood 91 and its collaborators.

JEOL is excited to share the insights and outcomes of its success meeting the qualification standards of AMS7032 build with the wider community. To facilitate this, the company will host a webinar on November 1st, offering an in-depth discussion of the results, capabilities, and future prospects of this cutting-edge AM system. Furthermore, JEOL will be actively participating at Formnext 2023, providing an opportunity for industry professionals to experience the JAM-5200EBM firsthand.

July 24, 2023, M&M 2023 Minneapolis, MN -- JEOL introduces two new Scanning Electron Microscopes this week at M&M 2023 in Minneapolis. The new SEMs incorporate the next level of intelligent technology and automation for ease of operation and fast, high-resolution imaging and analysis. These new-generation SEMs make it easy to acquire data for all specimen types.

Both new SEMs feature “Simple SEM” for automatic image collection at multiple locations, magnifications, and conditions, Live EDS analysis, Live 3D microscopy, automatic large-area analysis with ZeroMag software, Montage for large area mosaics, and automatic functions from alignment to focus for fast, clear, high-resolution images.

The new JSM-IT710HR SEM is a compact, versatile Schottky Field Emission SEM that delivers large probe currents while maintaining a small probe, making it ideally suited for higher resolution needs. A large specimen chamber and both High and Low Vacuum operation allow a wide variety of specimen types to be imaged and analyzed in their native state.

The new JSM-IT210 InTouchScope™ SEM is a compact microscope with easy, automated workflow features including Specimen Exchange mode that guides a new operator step-by-step from sample introduction to ideal imaging and analysis conditions.

JEOL has a complete range of Scanning Electron Microscopes ranging from the popular NeoScope tabletop SEM to its flagship ultrahigh resolution field emission SEM. JEOL offers applications and service support for all of its Electron Microscopes and scientific instruments, with over 70 years of expertise in electron optics.

Peabody, MA – As many legacy NMR instruments are no longer eligible for service from major players that have exited the space, members of the scientific community are faced with a choice: Keep their magnet and upgrade their console to the latest software or buy an entirely new system.

Upgrading an existing NMR console outfits the instrument with the latest technology and yields increase performance identical to that of a new system. Because the lifespan of a magnet far outlasts the console operating the instrument, this is a great way to save on costs and make full use of their magnet.

\“Replacing the console on the older NMR system is an affordable option to get the most out of existing NMR setup since one will have an opportunity to use newer probes, sample changers and modern applications,” shares Dr. Timothy Bergeron. “This will expand the range of NMR methods one can use and it will improve sample-to-sample throughput.”

Fortunately, JEOL is offering an NMR Console Upgrade Initiative, which offers discounted pricing for qualifying instruments. Those who are curious to learn if they qualify for the program can check out the digital NMR Console Upgrade Guide.

JEOL, Ltd. began manufacturing and selling NMR instruments in 1959. JEOL USA, Inc., a wholly owned subsidiary of JEOL, Ltd., Japan, was incorporated in the United States in 1962. The company has 13 regional service centers that offer unlimited emergency service and support in the U.S.

Peabody and Andover, MA - Two towering JEOL Electron Microscopes stand ready to produce terabytes of valuable data for researchers at Generate:Biomedicines each day, who are accelerating drug discovery and development of novel therapeutics using machine learning and generative artificial intelligence. The two Transmission Electron Microscopes, the JEOL CRYO ARM 200 and CRYO ARM 300 are used in structural biology, and at Generate:Biomedicines they will be used to capture atomic resolution details of proteins that will help provide therapies in the fields of oncology, immunology, and infectious disease.

JEOL has completed installation of the two CRYO ARMs at Generate:Biomedicines’ laboratory space in Andover, Massachusetts. The new facility expands beyond the company’s Somerville, Mass headquarters to specifically house their microscopy labs. Generate:Biomedicines unveiled the new CryoEM facility in June. JEOL will provide dedicated applications support and continue to work closely with Generate:Biomedicines scientists to integrate the advanced microscopes into their fast-paced research programs. JEOL, with USA headquarters nearby in Peabody, MA and corporate headquarters in Akishma, Japan, has been producing cutting edge electron microscopes for more than 70 years, advancing technology that has important ramifications in the life sciences as well as the materials sciences. 

Adam Root, Vice-President of Protein Sciences at Generate:Biomedicines, is excited about how the CRYO ARMs will be used to computationally design biotherapeutics. “We’ve built this facility to perform CryoEM at scale, adding structure determination to our ‘build-test-learn’ cycle and to continually advance our computational protein generation capabilities,” he says.  Their process allows them to rapidly visualize, at the atomic scale, the binding of computationally-designed drug candidates to any disease target, he explains. Instead of relying on a purely trial-and-error solution to disease, they will be able to leverage this structural data to propose entirely new therapeutic protein solutions with intent. 

“We will be pushing the CryoEM envelope,” adds Ed Brignole, Senior Director of CryoEM, “The two biggest evolutions in structural biology are the result of CryoEM technology and machine learning for predicting and designing protein structure. We are at the intersection putting the two together.” 

In keeping with the mission at Generate:Biomedicines, Ed adds, “We’ve studied millions of proteins and learned the general rules by which nature encodes function. From this knowledge we can generate novel medicines with specific therapeutic functions. We call this breakthrough Generative Biology. This is a fundamental shift in what’s possible in the field of therapeutic development, and we are incredibly excited as we realize the breadth of its potential.”

CryoEM methodology has been successfully applied to study therapeutic targets such as viruses, membrane proteins, and components of the immune system. The ability to capture the structure of biomolecules with CryoEM is key in understanding how these protein systems function, or malfunction in the case of disease, as well as in identifying potential drug-binding targets for therapies. In the last decade, the field of structural biology was revolutionized with the advent of direct detector cameras and highly stable, automated cryogenic electron microscopes propelling CryoEM into becoming one of the most widely used tools in structural biology. The dramatic evolution of the method was celebrated in 2017 with the Nobel prize in Chemistry awarded to Richard Henderson, Jacques Dubochet and Joachim Frank for each of their contributions to the field.

Generate:Biomedicines was founded by Flagship Pioneering after two years of foundational research in its Labs unit and launched in 2020. The proximity of Generate:Biomedicines’ CRYO ARMs and JEOL’s USA headquarters lends itself naturally to cooperation between JEOL USA scientists who have ready access to the high-end research microscopes to understand their application in the field and to optimize their abilities. 

“Generate:Biomedicines’ goal and strategy is an unparalleled undertaking in the field of medicine. JEOL USA is extremely proud to be part of the journey that Generate:Biomedicines will undertake to develop novel therapeutics that will greatly benefit mankind” says Jaap Brink, CryoEM Product Manager at JEOL USA.
 

(Peabody, MA and Pittsburgh, PA) -- JEOL USA and Cumberland Additive, Inc. (CAI) are pleased to announce that Cumberland’s Neighborhood 91 facility in Pittsburgh will be the first installation in North America of JEOL’s new Electron Beam Melting (EBM) Powder Bed Fusion (PBF) system. This new metal 3D Printed E-Beam system will expand capabilities, primarily for serial production of parts.

CAI is a trusted AM leader who manufactures prototypes through serial production of parts, supporting the aerospace, defense, space, and energy markets. Additional services offered at Cumberland include DfAM (Design for Additive Manufacturing), engineering, post-processing and quality inspection. JEOL is a well-known leader in the field of electron optics. The company introduced the new E-beam metal 3D printer to the North American market at Rapid TCT in May 2022 and garnered much interest in its display of serially built nested parts and a lightweight yet strong titanium electron beam column, just a few examples of parts it has produced.

The collaboration between the two companies brings JEOL new opportunities to demonstrate the unique abilities of the new EBM system in a dedicated environment for Additive Manufacturing. Cumberland is an AS9100D & ITAR-certified company with established processes and procedures that meet rigorous serial production requirements.

“We are delighted to align with CAI’s existing customer base and expansion strategy with aerospace, medical, and energy industries, and to showcase the production quality and reliability of our 3D printer that will be centrally located at Neighborhood 91, the first fully integrated production campus dedicated to additive manufacturing,” said JEOL USA President Robert Pohorenec. “In addition to being a centralized resource for the AM industry, Neighborhood 91 attracts collaborative academic research opportunities and workforce development at world-class universities like Carnegie Mellon and University of Pittsburgh.

“The past year has been significant for JEOL’s Additive Manufacturing group in the US,” Pohorenec continued. “We are currently pursuing AM-specific aerospace Fusion-Based Metal Additive Manufacturing qualifications that will validate the robustness and reliability of JEOL designed hardware.” 

John Jenkins, President of Cumberland Additive emphasized this new partnership: ”Cumberland is excited to partner with JEOL to bring in this new state-of-the-art, electron beam technology that promises cost effective and efficient manufacturing, with a diversity of material offerings for our customers. We are honored to be the first North America partner location for this exciting new technology.”  

JEOL’s EBM 3D printing technology began in 2014, derived from the company’s decades-long expertise in the development and production of advanced electron optics technology used for research and industrial applications, including electron microscopes and e-beam lithography tools with unique vacuum technology. The JEOL EBM 3D printer is designed for serial production with maximum uptime. Emitter lifetime is guaranteed over 1500hrs, which will give CAI confidence in their ability to provide timely solutions to their customers. Another key differentiator in JEOL 3D printing technology is the EBM’s clean, helium-free production environment that prevents smoke events and powder scattering.  At this time the materials that can be printed are Ti6Al4V, Nickel Alloy 718, and pure copper.  

The key to keeping AM production running smoothly is a reliable manufacturing tool backed by timely on-site repair. In addition to its reliable performance, the new EBM system is supported by JEOL’s nationwide field service support group of over 180 engineers with an average of over 10yrs experience in electron optics and vacuum technology.

About Cumberland Additive, Inc.

Cumberland Additive, Inc. began as Directed Manufacturing, Inc. in 2006. The company achieved steady growth throughout multiple markets, expanding manufacturing capabilities from polymer prototyping to serial production of metals and polymers on mid and large-format printers. Under new ownership as of May 31, 2019, Cumberland Additive is showcasing our expertise in additive manufacturing, providing engineering services and turn-key production using Powder Bed Fusion Technology in metals and advanced polymers. Cumberland is advancing 3D Printing by building trust with our partners through proven additive manufacturing experience, and a laser focus on technical data that is supported by repeatable quality and on-time delivery. Learn more at CumberlandAdditive.com.