The impact of cryo-EM has been so profound that it is predicted to surpass X-ray crystallography as the predominant structural biology method by 2024.
Cryo-electron microscopy is an imaging method that has revolutionized the recording 3D images of the structures of proteins.
Cryo-electron microscopy (cryo-em) and transmission electron microscopy (TEM) share many similarities, but their main difference is in sample prep.