JEOL USA Press Releases

JEOL USA Press Releases

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JEOL USA Press Releases

(November 8, 2018, Peabody, Mass.) --  JEOL has achieved a major expansion in the quantitative and statistical analysis capability of its Nuclear Magnetic Resonance Spectrometers (NMR) through collaboration with the developer of the revolutionary CRAFT (Complete Reduction to Amplitude-Frequency Table) data processing technique.
 
In conjunction with the recent JEOL DELTA NMR software release 5.3.0, CRAFT for DELTA V1.0 provides direct time domain-to-spreadsheet analysis, allowing for more objective extraction of quantitative information for compounds of interest, provides statistical analysis for metabolomics, reaction monitoring, or quality control.  Peaks that are too close to effectively quantify by traditional integration are completely resolved sinusoids in the time domain with separate information of frequency, amplitude, phase, and decay rate available as numbers in a table.
 
Pioneering work for CRAFT direct time-domain analysis of NMR data was begun by Dr. Krish Krishnamurthy and first published in 2013, and the work was extended to 2D NMR in 2016.  By utilizing Bayesian analysis of the time domain spectrum, CRAFT bypasses many issues brought about by Fourier transform to a visual frequency dimension. 
 
“The integration of CRAFT with DELTA version 5.3 software allows the JEOL NMR user to automatically and efficiently extract the best amplitudes and frequency from NMR data,” said Dr. Mike Frey, NMR Product Manager.

For more information, downloads, and technical support, visit jeolusa.com/CRAFT.



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