JEOL USA Press Releases

The introduction of direct electron detectors significantly improved the signal-to-noise ratio of electron micrographs, resulting in a marked enhancement in the quality of cryo-electron microscope (EM) reconstructions (now referred to as the “resolution revolution”).

This approach, along with advances in image processing and data collection, has pushed the resolution of single-particle cryo-EM reconstructions into the range where the electron source could become a limiting factor. This in turn has led to the reconsideration in cryo-EM of alternatives to the standard Schottky field emission gun (FEG), such as the cold FEG, owing to their superior coherence.

Despite the known benefits of the cold FEG over thermally assisted FEG, practical limitations prevented its use in cryo-EM until JEOL’s CryoARM microscope series was developed. Cold FEG was initially used on 300 kV cryomicroscopes to push the frontier of attainable resolution, ultimately resulting in cryo-EM reconstructions at “atomic resolution” where individual atoms are visible as separated spheres of density.

Following this success, attempts have been made at using the cold FEG source on 200 kV cryomicroscopes, which are generally smaller and less expensive, to see how far the tighter energy spread would allow the resolution to be pushed on this more accessible instrument.

In this webinar, the speaker will present results from a cold FEG-equipped CryoARM200 microscope that demonstrates how 200 kV data can be used to produce sub-2Å structures for a range of samples. The resolution of the reconstructions is comparable to that obtained from the more expensive state-of-the-art 300 kV microscopes.

All of the results described in the webinar are from data collected in an automated manner using the open-source software SerialEM. The familiarity that many users have with SerialEM, as well as its overall openness and ease-of-use, make obtaining high-quality data on this platform possible even for users who do not have extensive experience using a CryoARM microscope.

Register for this webinar today to gain insights into cryo-electron microscopy and how the integration of cold FEG technology in JEOL’s CryoARM200 microscope is revolutionizing cryo-EM.

Join Alan Merk, Electron Microscopist, Leidos Biomedical Research, for the live webinar on Monday, September 30, 2024, at 2pm EDT (11am PDT).

For more information, or to register for this event, visit Exploring the Range of Electron Microscopes: Resolution, Size and Users.

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The JSM-IT810 series Ultrahigh Resolution FE SEM made its debut at the Microscopy and Microanalysis 2024 conference in late July. This debut included live demonstrations for those in the market for an analytical ultrahigh resolution FE SEM.

This new platform is where versatility meets high spatial resolution and ease-of-use with the next level in JEOL’s intelligent technology for imaging and analysis at the nanoscale. Powerful software with automation built-in, enables seamless acquisition of data from observation to elemental analysis and reporting.

The JEOL NEOENGINE® electron beam control system and advanced auto functions provide fast and clear transitions from high resolution imaging to high current analysis without sacrificing performance. Capabilities include up to 2,000,000X magnification and accelerating voltage range from 0.01 to 30kV making it possible to acquire outstanding detail of nanomaterials or biological nanostructures.

New No-Code automation workflows come standard and make it very easy to achieve high throughput results. It is possible to automate the collection of images and analyses under multiple beam settings, positions and detectors without user intervention. Enhance efficiency and productivity with these new automation routines.

Equip with JEOL’s embedded Live EDS allows for direct monitoring of chemical composition during imaging.

Novel segmented detector options are available for Live 3D surface reconstruction for enhanced viewing of complex surfaces.

To experience the new capabilities or explore solutions that meet your work, customers are invited to contact JEOL USA.

JEOL (President & CEO Izumi Oi) announced the release of the "ROYAL PROBE™ AUTOMAS", a high-throughput solid-state NMR probe for nuclear magnetic resonance (NMR) systems, on 1st July 2024.

The ROYAL PROBE™ AUTOMAS is the successor to the AUTOMAS probe, which was launched in 2018 as a high-throughput solid-state NMR probe.

The AUTOMAS probe, in combination with the NMR software Delta, the Auto Sample Changer (ASC), and the Auto-Tuning Unit, allows multiple samples to be measured in series.

In addition to the basic functions of the AUTOMAS probe, the ROYAL PROBE™ AUTOMAS adds new features such as a seamless tuning range with the slider unit, automatic magic angle adjustment, and an extended measurement temperature range. These improvements dramatically enhance ease of use and make solid-state NMR measurements more accessible.

JEOL Ltd. (President & CEO Izumi Oi) announced the release of High Sensitivity COOL Probe "SuperCOOL MARVEL" for Nuclear Magnetic Resonance, NMR, on July 1st, 2024. Its sales are scheduled to begin in October 2024.

SuperCOOL MARVEL is the fourth generation of the SuperCOOL probe series, which was launched in 2013. The SuperCOOL probe series suppresses thermal noise and enables highly sensitive NMR measurements by cooling the RF coil and preamplifier to liquid nitrogen temperature. This product not only utilizes the low-temperature cooling technology know-how that we have cultivated over many years, but also achieves a significant improvement in sensitivity by completely redesigning the electrical circuitry inside the probe.

SuperCOOL MARVEL, which can measure low noise and high sensitivity, is a multi-nuclear probe capable of measuring not only common nuclei such as 1H and 13C, but also nuclei such as 19F and 31P. It is highly effective in measuring samples that decompose or change quickly, as well as trace samples that are difficult to obtain.

JEOL (President and CEO: Izumi Oi) announces the release of the new electron microscope JEM-120i developed with the concepts of "Compact", "Easy To Use", and "Expandable" on May 30, 2024.

Electron microscopes are utilized in a wide range of fields from biotechnology to nano technology, polymers, and advanced materials. With the expansion of application, usages are also expanding, which requires a tool that is easy-to-use for research and testing purposes. To satisfy such needs, the JEM-120i has evolved into a next-generation microscope that is easy to use, from operation to maintenance, for both beginner and experienced users.

Main Features

Compact

The JEM-120i adopts a totally new appearance and compact design that fits any installation location. The footprint has been reduced by more than 50%, and the volume occupied by the instrument is less than one-third of that of conventional models, enabling effective use of space. The instrument height is lower than 1,800 mm, which fits just about any installation room.

Easy to Use

The enhanced TEM control system and fully automated apertures eliminated the need for switching the magnification mode and selecting an aperture. The JEM-120i provides seamless observations from low to high magnification.

It takes only 4 steps from loading a specimen to completing an observation. After inserting the specimen holder, clicking the Start Button automatically performs observation preparation operations such as voltage increase and emission start. A wide area image is captured at the same time, and clicking the target field of view will complete the stage movement. Standard "Butler mode" assists data acquisition. Even a beginner can capture data easily.

Expandable

In addition to the standard multi-function camera, a bottom-mount camera of higher pixel count can be selected as an option.

Attachments such as the scanning image observation function (STEM), elemental analysis function (EDS), and cryo observation function can be applied, regardless of instrument configuration. The instrument can be expanded at any time to meet the changing needs of microscopy over time.

The proven scripting function (PyJEM) with the high-end models, can create an algorithm for automation. The automation can increase the utilization rate of the instrument and improve data output efficiency.

Main Specifications

*1 (HC) : High contrast configuration
*2 (HR) : High resolution configuration

JEOL is pleased to announce the introduction of a new CRYO-FIB-SEM, a Focused Ion Beam milling specimen preparation tool specifically designed for creating thin, frozen samples for Cryo-Electron Microscopy. The new system complements JEOL’s existing Cryo-TEM technology and provides a comprehensive solution for preparing and imaging vitreous frozen biological and biopolymer samples to be observed in the CRYO ARM 200 and CRYO ARM 300II Transmission Electron Microscopes. 

JEOL’s CRYO-FIB-SEM incorporates a liquid nitrogen cooling stage and a cryocooled specimen transfer mechanism for optimum specimen handling. The CRYO-FIB-SEM has a built-in sputter coating function, making it possible to perform conductivity coating, protective film forming, and FIB processing in a single system. 

Additionally, the workflow is based on JEOL's specially-designed CRYO ARM™ cartridge, allowing direct specimen transfer to the CRYO ARM™ after specimen preparation with the CRYO-FIB-SEM. A cryo-CLEM workflow using the CRYO ARM™ cartridge can be constructed using a cryostage manufactured by Linkam Scientific Instruments* and a fluorescence microscope manufactured by Nikon Solutions*. The stage coordinates of each instrument can be linked, so the orientation and position of the specimen can always be identified during specimen transfer between instruments.

Using Cryo-EM, researchers can capture high resolution details of proteins and biological specimens. With the advent of the resolution revolution for Cryo-EM beginning around 2010, JEOL CRYO ARM TEMs continue to solve structures previously reserved for traditional X-Ray Crystallography. Imaging data achieved at rapid speeds can be used to create 3D reconstructions of viruses and proteins. Data can also be interpreted using Single Particle Analysis, MicroED using electron diffraction from 3D crystals, electron crystallography, and tomography. 

“Along with the CryoARM, the CryoFIB now closes the loop in the cryo-EM process to provide a solution that is completely JEOL. This will streamline the entire cryo-EM process, from sample preparation to data collection,” said JEOL TEM Product Manager Dr. Patrick Phillips. 
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Peabody, MA | Nov. 2, 2023 – JEOL’s JAM-5200EBM Metal 3D Printer, a production ready Electron Beam Powder Bed Fusion (EB-PBF) additive manufacturing solution, has demonstrated the ability to meet the rigorous AMS7032 operational qualification (OQ) standards, while achieving the AMS7011 material requirements for Ti-6Al-4V alloy with post-deposition hot isostatic pressing (HIP). JEOL’s is the first EB-PBF machine known to meet the requirements of AMS7011 since they were first established on another EB-PBF manufacturer’s model.

The AMS7032 Operational Qualification Standard evaluates the ability of an AM powder bed fusion machine to consistently meet material specification requirements while maintaining process control and stability over several builds. To comply with the OQ procedures listed in AMS7032, three identical builds containing a large number of Ti-6Al-4V specimens in all three orientations and encompassing the entire JAM-5200EBM build envelope were made using reused powder that conformed to the AMS7015 specification. The specimens were then subjected to tensile testing, microstructure evaluation, chemical composition testing, radiography, and other tests to verify that they met the requirements of AMS7011. All required post processing and testing of the specimen was performed at a ISO17025 accredited laboratory.

The results of the testing not only demonstrated the high stability of the machine, but also revealed a key strength of this system: the JEOL JAM-5200EBM system produces material with excellent ductility and very low anisotropy. These results also indicate that designers should have significant freedom in how parts are oriented within the build envelope thus enabling greater DfAM flexibility and unlocking the potential for truly optimized designs.

“JEOL has provided metrology, analytical, and electron beam manufacturing instruments for over seventy years and understands that manufacturers must have confidence in their tools,” shares Bob Pohorenec, President of JEOL USA. “Meeting the AMS7032 operational qualification standard ensures manufacturers that the JAM-5200EBM is capable of producing aerospace-grade material with stable performance and meets all material specification requirements. This achievement is a testament to our commitment to quality and reliability.”

For businesses operating in the aerospace industry, our efforts greenlight a new alternative for 3D metal printing of parts essential in the manufacturing process. This grants them access to JEOL’s more than 70 years of electron beam expertise and grants the peace of mind that parts will meet compliance standards set in place to avoid failures.

JEOL is excited to share the insights and outcomes of its success meeting the qualification standards of AMS7032 and the material requirements of AMS 7011 with the wider community. The results were first presented at the Fall meeting of the SAE AMS AM Additive Manufacturing Metals committee, and the NRC Workshop on Advanced Manufacturing Technologies for Nuclear Applications, both held in October.

JEOL will further host a webinar on December 5th at 2PM ET, offering an in-depth discussion of the results, capabilities, and future prospects of this cutting-edge AM system. Furthermore, JEOL will be actively participating at Formnext 2023, providing an opportunity for industry professionals to meet their R&D team and learn more about their technology.

Pittsburgh, PA | Oct 4, 2023– JEOL, a world-renowned leader in electron optics and advanced technology solutions, proudly announces the arrival of the JAM-5200EBM Electron Beam-Powder Bed Fusion system to Cumberland Additive located at Neighborhood 91, the advanced manufacturing production campus at Pittsburgh International Airport. JEOL's leadership joined the Cumberland team this week to formally introduced the JAM-5200EBM to invited guests.

The JAM-5200EBM made an impressive debut in North America as the system was fully operational within just six days of arrival, a testament to its engineering excellence. The JEOL team further demonstrated its capabilities by producing an AMS 7032 compliant build within three weeks of installation, generating valuable data on the system's performance and repeatability across various build geometries. The same JAM-5200EBM machine had already completed an operational qualification per AMS 7032 specification at its manufacturing factory site in Japan where the results demonstrated that the machine is capable of meeting AMS 7011 specification minimums for Electron Beam-Powder Bed Fusion machines.

Cumberland Additive CEO Dawne Hickton officially welcomed JEOL to the production floor in Neighborhood 91 commenting, “This collaboration with JEOL signifies a new era in advanced additive manufacturing at Neighborhood 91. We look forward to harnessing the capabilities of the JAM-5200EBM E-Beam system and unlocking new possibilities in the world of materials science and 3D printing."

JEOL USA President Robert Pohorenec highlighted the significance of this partnership and the revolutionary advancements in additive manufacturing technology that JEOL is bringing to the table, “JEOL has been the leading supplier of electron-beam based imaging instruments and manufacturing tools for seventy-five years and has a well-established global customer service organization. However, we are a relative newcomer to the additive manufacturing machine market. The opportunity to collaborate with an additive manufacturing leader like Cumberland Additive in the Neighborhood 91 Additive Manufacturing campus provides us the perfect partner and location to introduce the JAM-5200EBM electron beam system in North America and to demonstrate our commitment to customer service.”

The JAM5200EBM system will initially focus on Titanium alloy, but the system is easily adaptable with the addition of a second hopper and feeder system. This will enable a seamless transition to produce components in Pure Copper and Nickel 718 alloy, expanding the range of possibilities for Neighborhood 91 and its collaborators.

JEOL is excited to share the insights and outcomes of its success meeting the qualification standards of AMS7032 build with the wider community. To facilitate this, the company will host a webinar on November 1st, offering an in-depth discussion of the results, capabilities, and future prospects of this cutting-edge AM system. Furthermore, JEOL will be actively participating at Formnext 2023, providing an opportunity for industry professionals to experience the JAM-5200EBM firsthand.

July 24, 2023, M&M 2023 Minneapolis, MN -- JEOL introduces two new Scanning Electron Microscopes this week at M&M 2023 in Minneapolis. The new SEMs incorporate the next level of intelligent technology and automation for ease of operation and fast, high-resolution imaging and analysis. These new-generation SEMs make it easy to acquire data for all specimen types.

Both new SEMs feature “Simple SEM” for automatic image collection at multiple locations, magnifications, and conditions, Live EDS analysis, Live 3D microscopy, automatic large-area analysis with ZeroMag software, Montage for large area mosaics, and automatic functions from alignment to focus for fast, clear, high-resolution images.

The new JSM-IT710HR SEM is a compact, versatile Schottky Field Emission SEM that delivers large probe currents while maintaining a small probe, making it ideally suited for higher resolution needs. A large specimen chamber and both High and Low Vacuum operation allow a wide variety of specimen types to be imaged and analyzed in their native state.

The new JSM-IT210 InTouchScope™ SEM is a compact microscope with easy, automated workflow features including Specimen Exchange mode that guides a new operator step-by-step from sample introduction to ideal imaging and analysis conditions.

JEOL has a complete range of Scanning Electron Microscopes ranging from the popular NeoScope tabletop SEM to its flagship ultrahigh resolution field emission SEM. JEOL offers applications and service support for all of its Electron Microscopes and scientific instruments, with over 70 years of expertise in electron optics.

Peabody, MA – As many legacy NMR instruments are no longer eligible for service from major players that have exited the space, members of the scientific community are faced with a choice: Keep their magnet and upgrade their console to the latest software or buy an entirely new system.

Upgrading an existing NMR console outfits the instrument with the latest technology and yields increase performance identical to that of a new system. Because the lifespan of a magnet far outlasts the console operating the instrument, this is a great way to save on costs and make full use of their magnet.

\“Replacing the console on the older NMR system is an affordable option to get the most out of existing NMR setup since one will have an opportunity to use newer probes, sample changers and modern applications,” shares Dr. Timothy Bergeron. “This will expand the range of NMR methods one can use and it will improve sample-to-sample throughput.”

Fortunately, JEOL is offering an NMR Console Upgrade Initiative, which offers discounted pricing for qualifying instruments. Those who are curious to learn if they qualify for the program can check out the digital NMR Console Upgrade Guide.

JEOL, Ltd. began manufacturing and selling NMR instruments in 1959. JEOL USA, Inc., a wholly owned subsidiary of JEOL, Ltd., Japan, was incorporated in the United States in 1962. The company has 13 regional service centers that offer unlimited emergency service and support in the U.S.