Analytical Instrument Documents

What does a mass spectrometer do? What are mass spectrometers used for? What does the mass tell us? How does a mass spectrometer work?

Several different definitions of resolution are used in mass spectrometry. It is useful to understand the distinctions between the different definitions to understand the characteristics of different mass spectrometers.

The JMS-S3000 "SpiralTOF™" is a MALDI-TOFMS that incorporates an innovative SpiralTOF ion optics system. The JMS-S3000 is available with a TOF-TOF option that can acquire high-energy collision-induced dissociation (CID) product ion spectra for monoisotopically selected precursor ions.

High molecular weight polymers are often MS-silent due to their inherent high dispersity (DM) or detected in the high mass range with low resolving power. An "on-plate" alkaline degradation has thus been developed as a sample pre-treatment on the MALDI target with tenths of ng of polymer to cut long industrial polyester chains into short oligomers amenable to MALDI-HRMS.

The JMS-S3000 "SpiralTOF™" is a MALDI-TOF MS incorporating an innovative SpiralTOF™ ion optics system. JEOL's patented technology achieves a spiral ion trajectory of 17m within a compact 1m space.

The JMS-S3000 SpiralTOF has a unique 17m flight path that offers then highest resolution MALDI-TOF MS system currently available. However, ions with a very short lifetime or that undergo spontaneous dissociation during their flight cannot be detected by the SpiralTOF (or a conventional reflection TOF). To address this situation, the SpiralTOF with Linear TOF option can be used for the high sensitivity analysis of intact proteins.

Diesel Fuel Analysis by GCxGC/EI (Hydrocarbon Classification); Biomarker Analysis by GCxGC/PI (Target Analysis using 2D EICC); Type Analysis by GCxGC/FI (Hydrocarbon Type Analysis); Synthetic Polymer Analysis by Pryolysis GCxGC/EI and FI (Unknown Compounds Analysis in Nylon 66); Additives Analysis by Pyrolysis GCxGC/EI and FI (Targeted Additives Analysis in Nitrile Butadiene Rubber); Natural Polymer Analysis by Pyrolysis GCxGC/EI and PI (Powerful Separation of the Main Components in a Japanese Lacquer Film); Soluble Organic Fraction Analysis by GCxGC/EI (Analysis of PAHs in Exhaust Gas); Electronic Waste Analysis by GCxGC/EI and Negative CI (Halogenated Compounds Analysis); Aroma Oil (Fragrance) Analysis by GCxGC/EI and FI (Molecular ion detection for Alcohol compounds); Sebum Analysis by GCxGC/EI (Pharmaceutical application)

Hemp is a strain of Cannabis sativa that has multiple industrial uses including paper, plastics, woven goods, and even food. While certain strains of Cannabis sativa are well-known for their use as a recreational drug due the presence of the psychoactive compound tetrahydrocannabinol (THC), hemp strains are defined by the U.S. federal government as those that contain less than 0.3% THC.1 Additionally, hemp strains typically contain more cannabidiol (CBD),2 which was recently approved by the FDA to treat certain types of epilepsy, and is currently being investigated as a medical treatment for other afflictions.

Introduction: In recent years, polymer materials have become more complex due to increased composition and diversification so that a one-sided analysis is insufficient and multifaceted observations and analyses are required. In response to this need, JEOL has engaged in applied research under the keyword of "YOKOGUSHI" (multifaceted cross-instrumental) using various instruments organically. In this Urushi Note, multifaceted analysis methods for polymer materials are illustrated using the examples of natural lacquer (urushi) analysis.

Some low-grade, inexpensive NMR sample tubes have large warpage, low wall thickness uniformity, and large distortion, which may adversely affect the resolution. The effect of low-grade sample tubes, such as disposable ones, on the resolution is small in low-field NMR, but it may be noticeable in high-field NMR. In addition, some disposable sample tubes are thicker or thinner than the nominal value and will not fit in the sample holder.